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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2464477aebea54a437a39f9adf15a481727fec052c2473af5648d295c7fe7d4' 
  AND token = 'gy4uBf3e3mPdd5P2HQrcKuxHdLm1pWf9PeS2GjcpMA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}