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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2419f462fa955724def9b8e5e70ccee835e2f00073c4e031fbb70eee22555737' 
  AND token = 'rDLrfEJX7YTr65tJwnmJxg+EQtsqAW5TEcNzePABQp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}