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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cae8650a2d5b1aca964bcb96d607e0e6207b2cd7af707493026bf26e3a0000' 
  AND token = '+fx/zN05jFAOKdCY0YQIwYAT6WXfAVYscRHPslGGa4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}