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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c29af25761dc2c22097e0bd35826322c9b3dc3ed4aabf71085b19101892131bf' 
  AND token = '8E/mjh1ZFluWDhXj7AD0gueTMPJ9rYoQFjcWCfCEgBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}