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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76cc8253990ebaa44611967112d7fb0a63f6c3da21cef1b47063c17c1e29e65b' 
  AND token = 'EK5ZFnd+tZPNqHk6E5duw/WKGtykqOmOp37+bDRiP6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}