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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0d2d45218826525b4bab239f740bc612be1885f439881371a6c8da1a262a96' 
  AND token = 'RSf3iuxg3o/TQkPtN7n9XEOC/XnmJU+X3bm64SepSr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}