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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e170baf3e9ba0dad50f737c0042d5f07be9b9c5c0901e4e3b371aec5e50d720' 
  AND token = 'G6I2U5L7qYFIh1srkZ3hRaFOdvvQVaTujCnl0/sioYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}