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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4acaf183fddb29597eddcbdbf74aa0a0aa97ca64a24efbe1537d04ddb75f38c5' 
  AND token = 'yuOPNYN7NMTtqiPH1hZMleHaaQ5PpmoxcXj4H9uJILo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}