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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f160633aa2f425ce425e032878e82168620afe3bb329cb9e42b1354a5dfd01' 
  AND token = 'UyqFI1XCFvCo30j6DkBcipDePgXIDCXtjc/R3ZB03r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}