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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46b0f2c21be5c18d302a0b6869f441480433f6f86309059c61436a304584c69' 
  AND token = '4k4hrT+RY5+EWPBUybvOvqkBzAHfRanWqxW5saO4VJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}