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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ee54ec1e8f68e20bbb34aa89b08ded1f2eb23a8bb5c2f97721c86931e192c8f' 
  AND token = 'a7x+C2c0zYRWAeby4Hm6GlQb7a3EXk3rqlBCLeRwLQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}