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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e39b7e2f5e129cc22b91d0e38f303edaf459fbc18ea2e18a38e3a53cfec79f8' 
  AND token = 'GxCP85BCldA3mDakQCZiI/M8mtI09bwtBz3jJXv2gL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}