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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b214b78d024edb003bf8812a806a87bf5dfa258f09e7adb6007b3c4dee9be480' 
  AND token = 'e05Pfb1+5qHCZuBMyxYcbEYgXJ7S/Mo6EnZTQMBLcvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}