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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd2ccab6bad3a11badcb7488ab06f550eff2d21bdcb0cef1e81f2ad99e2def1' 
  AND token = 'kUa5FT+X2krgHPYLwto8ng0DI7wdvEUF3F8Vn9Erm4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}