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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3204889c4dee3ec4888d611aa5cbc8fc74305eabebff10f2416a12043e2d4d9f' 
  AND token = 'Z+VP+GeoBsVBs1FvVJnSzOyLNXH/2uHTfIHAQfTNVMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}