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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc2c60a9ef65314babf67144590885bf86597660fe5f047a9d0abfcacf22dbe' 
  AND token = '+DM0PSX1EaMIy6UYKR3Zip/2w7dpXfk8jTL9+EKwWCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}