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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972726cf1c8df882bca5cf12658206df9e84cda5dab22203d7324c29315742bf' 
  AND token = 'AO2TxVONaONbZkzYXJHqH6wsul9XDxIiGiN+vcaQ1jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}