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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc3f829b0c253dd281f8625eaa2937387427c357c5d13fd67c9fbb7af9e0ad2' 
  AND token = 'hDedC5x+Y1AtgjY7wv0XcnRLa4ayY5B2hofZ9d9Du5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}