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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ffaaec27326d655b2508def8df6b45a8046da22386d606e80e951cea66e7428' 
  AND token = 'nDDOaPQp1Tm39hRiNo6sRGfW1vvxdD3ZcJ/qd51ng8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}