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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0199a77a1320690b6d74f7016822533af9bedcbb717e9b787f80e10706536270' 
  AND token = 'yCTfKDKEmfnR3KYiHy4vEQtlFdeHSZUzcGzoDqMbDH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}