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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0f15a80ac74a39915d0a0a63513eb8ce1bab8cda4117783d0b6efba27e6664' 
  AND token = 'PvdrgnjGwyc2pxOhPUBrs/Dkt3SoK1mC1/HB67bsUqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}