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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d510ca5693e5a03934198c71df8ba0e7fad21f1e78880b913674527da3af2f9' 
  AND token = 'FWpKEK6f5TYMScrSTi2+sl2uCHSX3kpYHF0XNynqzEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}