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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '964e96941ce87b8735670b883449fc9c7f9ad5c811425f6f8dcb16ebf13cf2fe' 
  AND token = 'hU0+N1NtRdObVcGk+GtlQgdnHszyS4vqU30S5OQiIYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}