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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d5ebfa7e60b8ba9779acc2f862ea2eae804520d8892f399610b5ddb724cf1f' 
  AND token = '5q2SHtCYE+PPhnkD/TuAk7iV3FKYSrTBRCWtR5pBKC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}