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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2335750998f5ffcc579709ffdd21c841b37f53ac9cf81dc109cd8d322c54438b' 
  AND token = 'ORwSyCAQMal++FozyrzAWlewLsMvycPYncM1SxJcXKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}