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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36c21e042e61d337b2dcd28636ad2b4105009788c0cae2124919fb37c9485bf3' 
  AND token = 'rNpp6aNippyq6BdOz0nN/IxzaX9O/VIxMpvghR1Zs4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}