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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42eaf5123961b79c7284a39c4fdd9a18faaaedf641acc2194e807bb150a3c671' 
  AND token = 'pUfcMopQ3m5v+5i2wzB1Bc19X7ZqAXc9isc2lzyFERs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}