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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fc9e4560ff4e26fc8fe7a6c9448b7bc8877d941ad7e830f2eb779002f4ff81' 
  AND token = 'VnsI7Q9RL/fTcDnTqqtWsG2Ns5qux1fpT26kRrZKRNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}