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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74bbcd5ab58fb4507318617b27b9911bf5627a2126f87ff24360de003e3b08a' 
  AND token = 'tGEX0vN7xKux45TwknyU17JAFKWb2MZSwXc0gpPgHcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}