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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffe5482d624ecdc25b6fcdd002cfe700e7ffd049016c5fadc218a80220cf3e14' 
  AND token = '/+UI6TBxXxR8jcILNmV99OP4U8cxGTnETj11LMYg5NM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}