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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2550cca7b644ca0463f03ff0d24085132ad1bb2dcf188a37a275e022beb1ad7b' 
  AND token = 'w2J6Xv1oC+ns/tNlf1j+hn9FbbQRYJI0N40sjX4Fh/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}