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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a7386a8c5c368e1fd4d4df021a660989457cf88243038084bedb4ad51c1a494' 
  AND token = 'H+xLwGlqR49joBv5z2Wn+IYMtbddnpmyBau8ilOyhrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}