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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ec02ef6840a078f59dce352af27e9e29831cb36ef37c41f7b065d0f1316e2a' 
  AND token = 'RD+9AraV4SOs3YYleNUDd+yvnPSvvi0nMXRY3v4FJ/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}