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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0ffc48e61ec300991a2adcd2fb22d100a2490ee14b2464ebc1230d27de725aa' 
  AND token = 'Njh8e8KEDZkzY//oLt1r1sINAIfKF3rPojPTQK0Kr1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}