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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2c44651ba8adbde486e00f4fdd59f0ea17e1f7bb469f00489777579e426ee6' 
  AND token = '73C5fd+BKP6X6wYkE6KcYLJzznp9+9tYLl0IMKpyFMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}