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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5f1b36e2c9850d0d0ef18d0f70ff58a19d3a6a3c1c33880afef0e01dffdf57' 
  AND token = 'bkOAaBAgSNRc0Q3pzlN52N6sCL+51IZuRYJmUP7vCh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}