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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f933bec81512b02ce562973cad93b86aceccdb8d420079e805c6b61c7be368' 
  AND token = 'J2/lmfCnIrpjv/DA/AbLgbSubNrOORYr69Ar6HLg+Y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}