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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a2135b3dc2d769f7b1b8ec0d99070b55e9be0fd0df6e83072acaa8d205a2070' 
  AND token = 'xSJYUeoLsD6QKAopfOVpdtS73MO4XrYTRnb43F5KMDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}