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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ad0bd2c16f1719f44c164551e65ae4fd6b0ece86dd22e77ef4be1325297b43' 
  AND token = 'EA2yzVpq9YZuK9ClseJgCTpgppaV8hlgIGcrO99Evw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}