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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a60bdb3b667c57582db88fa9c67c83144ab8f5f8bf6fd71ff7f467247417de81' 
  AND token = 'CQEshFv3eD1aFkHhpVPUjE2NSYWZYiER3VoEY2rd2Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}