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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '718ad3a52778dbda97595e7104703f436e18aa5aa7945f1afafed60acbe249c1' 
  AND token = '2HW+LHNsYa4BNketezmn7Gob1XnuD2rYv4jOkzOerhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}