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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14cf420cef955f6516c87c33b78e10816d6a59f1c15d617cd70f093f2d834d2' 
  AND token = '175v5DegAM2+mOw+3lFA5btwVN053kZHkUByDsa9l7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}