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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e2961bb6243e1882889a7a121784916e53fa64d7cbc19fb79c6953eb4d6f61' 
  AND token = '43UXSCYwwfD8Xc3ked72KnSBwnQ9tYBzTO3q606iIOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}