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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72baecd34ce436d8bf592240420b3a1dfda1f5c4542325f5bbf47bc9e18948c9' 
  AND token = 'pJqiBndfDdhf4SPU+0YRM+/JFXaQN3tj9BPND1YQGK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}