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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59446a4f2ea8ebe59cf5b29a8ec73e4e3c6cb14f748b8937c0f1cdc822aa7e48' 
  AND token = 'T07p2Vm/MMJPfSpgkizA0RyvpPDvs4EccuFaGbSwVGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}