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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2321fe25724deda0976c8a525385dc151edb5a977d837195e79867ca6f6325' 
  AND token = 'LERJBA+WtvDth1X4aVQQHznefk0I8WIK25xWUN3FK6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}