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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b18460dc9b2738ba15f4018fc98383d359a4049eceb09d63a97d23f30910d1' 
  AND token = 'n0/j3ZiHtXc/Ipeh8pbHTTUcByo/cSMs9JoqC/cCTM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}