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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b01a4b180510f128dcd3e2a864816f4397ed834076362afeffab6fdda221d61' 
  AND token = 'dxgswzmnxkbzt5oOGbVK8NxkPH8Bz6DvaWmCwIuDAq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}