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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6949c7f2ef37340e4dd618c06cd518e3914fd0d01c023f839713bba065b647db' 
  AND token = 'zOVwuyJ7FEV1uwMOMt7SjgbqZVHg3PPTsRlDfJ0Vlac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}