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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae4303dbdeed7946327c284a5fbe71144f4dff3ef4e01a2ef754ab8fc0df7ea' 
  AND token = 'x+UiehRC/LIPWuZeDaQ6hPhYYb/qFVofHSS72Z51YE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}